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The consensus report concludes that "Even though the data continues to be incomplete, National Assessment meeting individuals concurred that methadone tablets or Diskets dispersed as a result of channels other than opioid treatment programs most likely would be the central factors in methadone-associated mortality."[56]If mixed, monitor for QTc int
fentanyl, cyproheptadine. Possibly increases toxicity of the other by pharmacodynamic synergism. Modify Therapy/Observe Closely. Coadministration of fentanyl with anticholinergics may enhance risk for urinary retention and/or critical constipation, which can bring about paralytic ileus.If coadministration of CYP3A4 inhibitors with fentanyl is essen